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Moreover, GA has been shown to mitigate liver damage in rats exposed to dust, significantly reducing the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP), and altering the serum triglyceride (TG) levels, similar to the protective effects observed with PM2.5 exposure

The acute decrease in UMP/UDP/UTP levels that resolves despite continued TS inhibition supports the hypothesis that an increase in nucleotide salvage might be linked to our observed mitochondrial phenotypes

Importantly, such studies have not detected selenenic acid so far during the GPx cycle

La actividad antioxidante del GSH fue demostrada y descrita por primera vez en 1961, utilizando extractos de hgado de rata